May support glucose control and insulin sensitivity when a clinician identifies an appropriate metabolic indication; it is not a universal anti-aging prescription.
WEIGHT & METABOLIC HEALTH / PRACTITIONER-GUIDED
Metformin
Metformin is an established diabetes medication with a clear role for selected metabolic indications, while its use for healthy longevity remains unproven and off-label.Create account & prepare for review →Practitioner review required · A prescription is never guaranteed.
Strong evidence for approved metabolic uses; insufficient evidence that it extends lifespan in healthy adults.
Prescription required; longevity use is off-label
WHO MAY BE CONSIDERED
Eligibility starts with your complete health context.
- ✓A valid metabolic indication is established
- ✓Kidney function and acute-illness risks are reviewed
- ✓The goal and monitoring plan are explicit
WHAT A PRACTITIONER REVIEWS
The information that shapes the decision.
- →A1c, glucose pattern and clinical indication
- →Kidney and liver context
- →GI tolerance, vitamin B12 and interacting procedures or medicines
IMPORTANT SAFETY INFORMATION
Reasons treatment may not be appropriate.
- !GI effects and vitamin B12 deficiency can occur.
- !Kidney impairment, severe illness, hypoxia and contrast procedures can change safety.
- !Rare lactic acidosis risk requires appropriate prescribing and sick-day guidance.
ORIGINAL SOURCES